国际眼科纵览

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剥脱综合征与系统性疾病的相关性

阿不都热合买江 丁琳   

  1. 新疆医科大学,乌鲁木齐 830054
  • 收稿日期:2019-07-21 出版日期:2020-02-22 发布日期:2020-02-27
  • 通讯作者: 丁琳,Email: dinglin85600@163.com E-mail:dinglin85600@163.com

Relationship between exfoliation syndrome and systemic diseases

Abudurehemaijiang,Ding Lin   

  1. Xinjiang Medical University, Urumqi 830054, China
  • Received:2019-07-21 Online:2020-02-22 Published:2020-02-27
  • Contact: Ding Lin, Email:dinglin85600@163.com E-mail:dinglin85600@163.com

摘要: Exfoliation syndrome (XFS) is a complex age\|related disease in which flaky white floes deposit in the anterior chamber of the eye and other tissues in the eye, and cause glaucoma. Epidemiological studies showed that XFS increases risk of coronary artery disease, hypertension,cerebrovascular disease, abdominal aortic aneurysm, peripheral vascular disease, sensorineural hearing loss. The exact mechanism underlying the development of vascular complications in XFS remains poorly understood, although abnormal elastic fiber synthesis in vessel walls, elevated serum antiphospholipid antibody levels, increased oxidative stress, endothelial dysfunction and hyperhomocysteinemia are all hypothesized to play contributory roles.

Abstract: Exfoliation syndrome (XFS) is a complex age\|related disease in which flaky white floes deposit in the anterior chamber of the eye and other tissues in the eye, and cause glaucoma. Epidemiological studies showed that XFS increases risk of coronary artery disease, hypertension,cerebrovascular disease, abdominal aortic aneurysm, peripheral vascular disease, sensorineural hearing loss. The exact mechanism underlying the development of vascular complications in XFS remains poorly understood, although abnormal elastic fiber synthesis in vessel walls, elevated serum antiphospholipid antibody levels, increased oxidative stress, endothelial dysfunction and hyperhomocysteinemia are all hypothesized to play contributory roles.